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Impact of nuclear-mitochondrial hybridization on fitness and oxidative stress in Caenorhabditis briggsae and C. sp. 9
Yockey, Mason John
Yockey, Mason John
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[Fort Worth, Tex.] : Texas Christian University,
Date
2013
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Abstract
Mitochondria are organelles contained in eukaryotic cells, which produce energy. Mitochondria are unique for several reasons, one being that they contain a small genome of their own, distinct from the main genome contained within the nucleus. Proper co-ordination between the nucleus and the mitochondria is vital for the functioning of the cell. A study was recently performed on several hybrid strains of Caenorhabditis nematodes which contained nuclear DNA from one lineage and mitochondrial DNA from another. Their fitness was tested by examining their growth, reproduction, lifespan under oxidative stress in the form of 95% oxygen. Results from these experiments appeared to show these trends: growth was typically suppressed, reproduction diminished, and lifespan slightly extended by the oxygen stress. These results might indicate the presence of a mitochondrial hormetic effect in these organisms.
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Biology
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Hartman, Philip S.