Loading...
Impact of a short-term antibiotic cycle on glucose control in adults with overweight or obesity
Mrosla, Jessica
Mrosla, Jessica
Citations
Altmetric:
Soloist
Composer
Publisher
Date
2024-05-06
Additional date(s)
Abstract
Epidemiologic evidence suggests that antibiotic frequency increases insulin resistance and reduces glucose control. However, interventional human studies have produced conflicting results on the effects of short-term antibiotic cycles on glucose control, demonstrating either no effect or harmful effects on glucose control. Our study aimed to contribute to the current body of literature examining the effects of short-term antibiotic cycles on glucose control in order to better clarify and understand the accumulated exposure risk of chronic insulin resistance and glucose dysregulation. Despite a small sample size (n=11), a short antibiotic cycle (3 days of therapeutic dosge of Vancomycin) significantly increased serum fasting insulin (p=0.037) and fasting glucose (0.023) levels from baseline. Our study indicates that short antibiotic cycles can induce acute harmful effects and warrants for further research examining the chronic and accumulated risk of antibiotic exposures. Furthermore, this study highlights the need for research on methods to prevent acute antibiotic-induced glucose control disruption.
Contents
Subject
Health sciences
Nutrition
Glucose control
Insulin resistance
Nutrition
Glucose control
Insulin resistance
Subject(s)
Research Projects
Organizational Units
Journal Issue
Genre
Thesis
Description
Format
Department
Nutritional Sciences