Case series of acute appendicitis association with SARS-CoV-2 infection

Prichard, Charlsea; Canning, Matthew; McWilliam-Ross, Kindra; Birbari, John; Parker, William; Wasson, Lori; Hollingsworth, John W.

Publication

Case series of acute appendicitis association with SARS-CoV-2 infection

Prichard, Charlsea; Canning, Matthew; McWilliam-Ross, Kindra; Birbari, John; Parker, William; Wasson, Lori; Hollingsworth, John W.

Publisher

SpringerNature

Date

2021

Abstract

Background: Describe the indications for surgical interventions in asymptomatic patients with SARS-CoV-2. We are unaware of previous reports of an association between SARS-CoV-2 and acute appendicitis. Methods: We performed a single institution retrospective review of SARS-CoV-2 pre-procedure testing and indications for surgical intervention. Statistical comparisons were performed using Chi Square analysis or two-tailed Student T test. Results: We report a high prevalence of SARS-CoV-2 in both all testing and pre-procedure testing during the enrollment period. We observe a high prevalence of acute appendicitis among patients identified to be SARS-CoV-2 positive during pre-procedure testing and without recognized symptoms of COVID19. Conclusion: We report a previously unrecognized association between SARS-CoV-2 and acute appendicitis.