Now showing items 981-1000 of 1008

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    Assessing Mathematical Models of Influenza Infections Using Features of the Immune Response 

    Dobrovolny, Hana M.; Reddy, Micaela B.; Kamal, Mohamed A.; Rayner, Craig R.; Beauchemin, Catherine A. A. (2013-02-28)
    The role of the host immune response in determining the severity and duration of an influenza infection is still unclear. In order to identify severity factors and more accurately predict the course of an influenza infection ...
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    Neuroprotective Actions of Methylene Blue and Its Derivatives 

    Poteet, Ethan; Winters, Ali; Yan, Liang-Jun; Shufelt, Kyle; Green, Kayla N.; Simpkins, James W.; Wen, Yi; Yang, Shao-Hua (2012-10-31)
    Methylene blue (MB), the first lead chemical structure of phenothiazine and other derivatives, is commonly used in diagnostic procedures and as a treatment for methemoglobinemia. We have previously demonstrated that MB ...
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    The Selective Allure of Neuroscientific Explanations 

    Scurich, Nicholas; Shniderman, Adam (2014-09-10)
    Some claim that recent advances in neuroscience will revolutionize the way we think about human nature and legal culpability. Empirical support for this proposition is mixed. Two highly-cited empirical studies found that ...
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    The Pore-Forming Protein Cry5B Elicits the Pathogenicity of Bacillus sp. against Caenorhabditis elegans 

    Kho, Melanie F.; Bellier, Audrey; Balasubramani, Venkatasamy; Hu, Yan; Hsu, Wayne; Nielsen-LeRoux, Christina; McGillivray, Shauna M.; Nizet, Victor; Aroian, Raffi V. (2011-12-22)
    The soil bacterium Bacillus thuringiensis is a pathogen of insects and nematodes and is very closely related to, if not the same species as, Bacillus cereus and Bacillus anthracis. The defining characteristic of B. ...
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    The Effect of UV-C Exposure on Larval Survival of the Dreissenid Quagga Mussel 

    Stewart-Malone, Alecia; Misamore, Michael J.; Wilmoth, Siri; Reyes, Alejandro; Wong, Wai Hing; Gross, Jackson (2015-07-17)
    The rapid spread of quagga mussels (Dreissena rostriformis bugensis) has lead to their invasion of Lake Mead, Nevada, the largest reservoir in North America and partially responsible for providing water to millions of ...
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    Altered Nrf2 Signaling Mediates Hypoglycemia-Induced Blood-Brain Barrier Endothelial Dysfunction In Vitro 

    Sajja, Ravi K.; Green, Kayla N.; Cucullo, Luca (2015-03-25)
    Hypoglycemia impairs blood-brain barrier (BBB) endothelial function; a major hallmark in the pathogenesis of various CNS disorders. Previously, we have demonstrated that prolonged hypoglycemic exposure down-regulated BBB ...
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    Syringeal Specialization of Frequency Control during Song Production in the Bengalese Finch (Lonchura striata domestica) 

    Secora, Kristen R.; Peterson, Jennifer R.; Urbano, Catherine M.; Chung, Boah; Okanoya, Kazuo; Cooper, Brenton G. (2012-03-27)
    Background: Singing in songbirds is a complex, learned behavior which shares many parallels with human speech. The avian vocal organ (syrinx) has two potential sound sources, and each sound generator is under unilateral, ...
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    Incentive or Habit Learning in Amphibians? 

    Muzio, Rubén N.; Creydt, Virginia Pistone; Iurman, Mariana; Rinaldi, Mauro A.; Sirani, Bruno; Papini, Mauricio Roberto (2011-11-08)
    Toads (Rhinella arenarum) received training with a novel incentive procedure involving access to solutions of different NaCl concentrations. In Experiment 1, instrumental behavior and weight variation data confirmed that ...
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    Intraspecific Inversions Pose a Challenge for the trnH-psbA Plant DNA Barcode 

    Whitlock, Barbara A.; Hale, Amanda M.; Groff, Paul A. (2010-07-13)
    Background: The chloroplast trnH-psbA spacer region has been proposed as a prime candidate for use in DNA barcoding of plants because of its high substitution rate. However, frequent inversions associated with palindromic ...
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    Coinfections of the Respiratory Tract: Viral Competition for Resources 

    Pinky, Lubna; Dobrovolny, Hana M. (2016-05-19)
    Studies have shown that simultaneous infection of the respiratory tract with at least two viruses is common in hospitalized patients, although it is not clear whether these infections are more or less severe than single ...
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    BODIPY-BODIPY dyad: Assessing the potential as a viscometer for molecular and ionic liquids 

    Kimball, Joseph D.; Raut, Sangram L.; Jameson, Laramie P.; Smith, Nicholas W.; Gryczynski, Zygmunt; Dzyuba, Sergei V. (2015-02-10)
    A symmetrical BODIPY-BODIPY dyad with a diyne linker was prepared in two steps; the lifetime decay of this rotor appeared to correlate with the viscosity of the media, thus making this dyad a suitable small molecule ...
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    A homodimeric BODIPY rotor as a fluorescent viscosity sensor for membrane-mimicking and cellular environments 

    Raut, Sangram L.; Kimball, Joseph D.; Fudala, Rafal; Doan, Hung; Maliwal, Badri P.; Sabnis, Nirupama A.; Lacko, Andras G.; Gryczynski, Ignacy; Dzyuba, Sergei V.; Gryczynski, Zygmunt (2014-10-29)
    Fluorescence properties of a novel homodimeric BODIPY dye rotor for Fluorescence Lifetime Imaging Microscopy (FLIM) are reported. Steady state and time resolved fluorescence measurements established the viscosity dependent ...
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    A triazine-based BODIPY trimer as a molecular viscometer 

    Raut, Sangram L.; Kimball, Joseph D.; Fudala, Rafal; Bora, Ilkay; Chib, Rahul; Jaafari, Hana; Castillo, Marlius K.; Smith, Nicholas W.; Gryczynski, Ignacy; Dzyuba, Sergei V.; Gryczynski, Zygmunt (2016-01-06)
    Photophysical behaviour of a novel trimeric BODIPY rotor with a high extinction coefficient is reported. Steady state and time resolved fluorescence measurements established that the trimer could be used as a viscometer ...
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    Quantifying solvated electrons' delocalization 

    Janesko, Benjamin G.; Scalmani, Giovanni; Frisch, Michael J. (2015-05-21)
    Delocalized, solvated electrons are a topic of much recent interest. We apply the electron delocalization range EDR([r (vector)];u) (J. Chem. Phys., 2014, 141, 144104) to quantify the extent to which a solvated electron ...
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    Effect of ionic liquids on the conformation of a porphyrin-based viscometer 

    Jameson, Laramie P.; Kimball, Joseph D.; Gryczynski, Zygmunt; Balaz, Milan; Dzyuba, Sergei V. (2013-08-05)
    Structure of the cationic and anionic counterparts of ionic liquids has a significant impact on the conformational bias of the porphyrin rotor; an apparent correlation between the conformation and the viscosity of ionic ...
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    Effect of imidazolium room-temperature ionic liquids on aggregation of amphotericin B: A circular dichroism study 

    Jameson, Laramie P.; Dzyuba, Sergei V. (2015-09-17)
    The nature of the anion of imidazolium-based ionic liquids was found to control the aggregate-monomer equilibrium of amphotericin B. This is in contrast to aqueous solutions of inorganic salts and imidazolium-based ionic ...
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    Conformational preference of a porphyrin rotor in confined environments 

    Jameson, Laramie P.; Balaz, Milan; Dzyuba, Sergei V.; Kamiya, Noriho (2013-11-05)
    The amount of twisted conformation of a porphyrin rotor, when confined within ionic liquid reverse micelles, increased as compared to the neat solvents within a set of 1-alkyl-3-methylimidazolium ionic liquids. A similar ...
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    Interaction of BODIPY dyes with bovine serum albumin: a case study on the aggregation of a click-BODIPY dye 

    Jameson, Laramie P.; Smith, Nicholas W.; Annunziata, Onofrio; Dzyuba, Sergei V. (2016-05-09)
    The fluorescence of BODIPY and click-BODIPY dyes was found to substantially increase in the presence of bovine serum albumin (BSA). BSA acted as a solubilizer for dye aggregates, in addition to being a conventional binding ...
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    Fabrication and size dependent properties of porous silicon nanotube arrays 

    Huang, Xuezhen; Gonzalez-Rodriguez, Roberto; Rich, Ryan M.; Gryczynski, Zygmunt; Coffer, Jeffery L. (2013-05-14)
    A general method for the formation of a broad family of silicon nanotube arrays (Si NTAs) relevant to diverse fields - ranging from energy storage to therapeutic platforms - is described. Such nanotubes demonstrate a ...
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    The effect of nanocrystalline silicon host on magnetic properties of encapsulated iron oxide nanoparticles 

    Granitzer, P.; Rumpf, K.; Gonzalez-Rodriguez, Roberto; Coffer, Jeffery L.; Reissner, M. (2015-11-12)
    The purpose of this work is a detailed comparison of the fundamental magnetic properties of nanocomposite systems consisting of Fe3O4 nanoparticle-loaded porous silicon as well as silicon nanotubes. Such composite structures ...