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dc.creatorOnodera, Akira
dc.creatorYanase, Sumino
dc.creatorIshii, Takamasa
dc.creatorYasuda, Kayo
dc.creatorMiyazawa, Masaki
dc.creatorHartman, Philip S.
dc.creatorIshii, Naoaki
dc.date.accessioned2021-01-15T15:47:27Z
dc.date.available2021-01-15T15:47:27Z
dc.date.issued2009-10-23
dc.identifier.urihttps://doi.org/10.1269/jrr.09093
dc.identifier.urihttps://repository.tcu.edu/handle/116099117/43069
dc.description.abstractThe time spent as a dauer larva does not affect adult life span in Caenorhabditis elegans, as if aging is suspended in this quiescent developmental stage. We now report that modest doses X-irradiation of dauer larvae increased their post-dauer longevity. Post-irradiation incubation of young dauer larvae did not modify this beneficial effect of radiation. Conversely, holding dauer larvae prior to irradiation rendered them refractory to this X-radiation-induced response. We present a model to explain these results. These experiments demonstrate that dauer larvae provide an excellent opportunity to study mechanisms by which X irradiation can extend life span.en_US
dc.description.statementofresponsibilityHartman (BIOL)
dc.language.isoenen_US
dc.publisherOxford University Press
dc.rights.urihttps://academic.oup.com/journals/pages/self_archiving_policy_c
dc.sourceJournal of Radiation Research
dc.source.urihttps://academic.oup.com/jrr/article/51/1/67/923991
dc.subjectAging
dc.subjectC. elegans
dc.subjectDauer larvae
dc.subjectRadiation
dc.subjectBeneficial effect
dc.titlePost-dauer Life Span of Caenorhabditis Elegans Dauer Larvae Can be Modified by X-irradiation
dc.typeArticle
dc.rights.holder2010 Journal of Radiation Research Editorial Committee
dc.rights.licenseOxford University Press and the Journal of Radiation Research are the original place of publication. Authors of open access articles are entitled to deposit their original version or the version of record in institutional and/or centrally organized repositories and can make this publicly available immediately upon publication, provided that the journal and OUP are attributed as the original place of publication and that correct citation details are given. Authors should also deposit the URL of their published article, in addition to the PDF version.
local.collegeCollege of Science and Engineering
local.departmentBiology


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