dc.creator | Winters, Karen R | |
dc.creator | Montchamp, Jean-Luc | |
dc.date.accessioned | 2023-02-27T15:56:11Z | |
dc.date.available | 2023-02-27T15:56:11Z | |
dc.date.issued | 2022 | |
dc.identifier.uri | https://doi.org/10.3762/bjoc.18.154 | |
dc.identifier.uri | https://repository.tcu.edu/handle/116099117/57382 | |
dc.description.abstract | A series of P-stereogenic chiral phosphorus acids (CPAs) were synthesized to determine the requirements for efficient asymmetric organocatalysis. In order to eliminate the need for C2-symmetry in common CPAs, various scaffolds containing C1-symmetrical thiophosphorus acids were chosen. These new compounds were synthesized and evaluated in the asymmetric transfer hydrogenation of 2-phenylquinoline. Although the efficacy of the thiophosphorus acids was disappointing for this reaction, the work should be useful for developing structural design elements. | |
dc.language | en | |
dc.publisher | Beilstein Institut | |
dc.source | Beilstein Journal of Organic Chemistry | |
dc.subject | asymmetric | |
dc.subject | heterocycles | |
dc.subject | organocatalysis | |
dc.subject | phosphorus | |
dc.subject | synthesis | |
dc.title | Design, synthesis, and evaluation of chiral thiophosphorus acids as organocatalysts | |
dc.type | Article | |
dc.rights.license | CC BY 4.0 | |
local.college | College of Science and Engineering | |
local.department | Chemistry and Biochemistry | |
local.persons | All (CHEM) | |