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dc.creatorHefley, Brenna S.
dc.creatorAli, Arsalan A.
dc.creatorBhattacharya, Pradipta
dc.creatorHjortdal, Jesper
dc.creatorWalker, Maria K.
dc.creatorKaramichos, Dimitrios
dc.date.accessioned2024-09-25T21:35:56Z
dc.date.available2024-09-25T21:35:56Z
dc.date.issued7/3/2024
dc.identifier.urihttps://doi.org/10.1080/17469899.2024.2368801
dc.identifier.urihttps://repository.tcu.edu/handle/116099117/65956
dc.descriptionIntroductionKeratoconus (KC) is the most prevalent corneal ectasia in the world, and its pathogenesis is influenced by both ocular and systemic factors. This review explores the multifaceted associations between keratoconus and systemic health conditions, ocular characteristics, and various other environmental/exogenous factors, aiming to illuminate how these relationships influence the pathophysiology of the disease.Areas CoveredThis review will summarize the fundamental attributes of KC, review and discuss the systemic and ocular association of KC including molecular biomarkers, and provide an organized overview of the parallel alterations occurring within various biological pathways in KC.Expert OpinionDespite the substantial volume of research on keratoconus, the precise etiology of the disease remains elusive. Further studies are necessary to deepen our understanding of this intricate disorder and improve its management.
dc.languageen
dc.publisherInforma UK Limited
dc.sourceEXPERT REVIEW OF OPHTHALMOLOGY
dc.titleSystemic and ocular associations of Keratoconus
dc.typeArticle
dc.rights.licenseCC BY-NC-ND 4.0
local.collegeBurnett School of Medicine
local.departmentBurnett School of Medicine
local.personsAli (SOM)


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