Progress Toward Biodegradable Triazine Dendrimers Using Triazinyl Hydrazone Linkages

Abstract

This research aims to synthesize a triazine dendrimer with labile arms through the incorporation of hydrazone linkages. This dendrimer should be susceptible to hydrolysis in acidic conditions, be soluble in water, relatively non-toxic, and be degradable into molecules small enough for excretion. The synthesis uses trichlorotriazines as branching molecules and different types of diamines to connect the branches.