dc.creator | Ching N. R. | |
dc.creator | Alzghari A. K. | |
dc.creator | Alzghari S. K. | |
dc.date.accessioned | 2019-07-12T16:02:36Z | |
dc.date.available | 2019-07-12T16:02:36Z | |
dc.date.issued | 2018-08-13 | |
dc.identifier.uri | https://doi.org/10.7759/cureus.3133 | |
dc.identifier.uri | https://repository.tcu.edu/handle/116099117/26467 | |
dc.identifier.uri | https://www.cureus.com/articles/13678-the-relationship-of-ugt2b15-pharmacogenetics-and-lorazepam-for-anxiety | |
dc.description.abstract | Anxiety affects over 260 million people worldwide. Benzodiazepines are a class of agents used in combination with other therapies for the management of anxiety. Lorazepam is a commonly prescribed benzodiazepine metabolized by uridine 5'-diphosphate-glucuronosyltransferases. Herein, we discuss recent findings regarding the pharmacogenetics of uridine 5'-diphosphate-glucuronosyltransferase 2B15 (UGT2B15), lorazepam, and its role in the treatment of anxiety. | |
dc.language.iso | en | en_US |
dc.publisher | Cureus | |
dc.rights.uri | https://creativecommons.org/licenses/by/3.0/ | |
dc.source | Cureus | |
dc.subject | lorazepam | |
dc.subject | single nucleotide polymorphisms | |
dc.subject | anxiety | |
dc.subject | pharmacogenetics | |
dc.subject | ugt2b15 | |
dc.title | The Relationship of UGT2B15 Pharmacogenetics and Lorazepam for Anxiety | |
dc.type | Article | |
dc.rights.holder | Ching N R et al. | |
dc.rights.license | CC BY 3.0 | |
local.college | College of Science and Engineering | |
local.department | Chemistry and Biochemistry | |
local.persons | Ching (CHEM) | |