The Relationship of UGT2B15 Pharmacogenetics and Lorazepam for AnxietyShow full item record
| Title | The Relationship of UGT2B15 Pharmacogenetics and Lorazepam for Anxiety |
|---|---|
| Author | Ching N. R.; Alzghari A. K.; Alzghari S. K. |
| Date | 2018-08-13 |
| Abstract | Anxiety affects over 260 million people worldwide. Benzodiazepines are a class of agents used in combination with other therapies for the management of anxiety. Lorazepam is a commonly prescribed benzodiazepine metabolized by uridine 5'-diphosphate-glucuronosyltransferases. Herein, we discuss recent findings regarding the pharmacogenetics of uridine 5'-diphosphate-glucuronosyltransferase 2B15 (UGT2B15), lorazepam, and its role in the treatment of anxiety. |
| Link | https://doi.org/10.7759/cureus.3133
https://repository.tcu.edu/handle/116099117/26467 https://www.cureus.com/articles/13678-the-relationship-of-ugt2b15-pharmacogenetics-and-lorazepam-for-anxiety |
| Department | Chemistry and Biochemistry |
| Subject | lorazepam
single nucleotide polymorphisms anxiety pharmacogenetics ugt2b15 |
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