|Abstract||While science education aims for literacy regarding scientific knowledge and the work of scientists, the separation of scientific knowing from other knowing may misrepresent the knowing of scientists. The majority of science educators K-university are women. Many of these women are spiritual and integrate their scientific and spiritual ways of knowing. Understanding spiritual women of science would inform science education and serve to advance the scientific reason and spirituality debate. Using interviews and grounded theory, this study explores scientific and spiritual ways of knowing in six women of science who hold strong spiritual commitments and portray science to non-scientists. From various lived experiences, each woman comes to know through a Passive knowing of exposure and attendance, an Engaged knowing of choice, commitment and action, an Mindful/Inner knowing of prayer and meaning, a Relational knowing with others, and an Integrated lifeworld knowing where scientific knowing, spiritual knowing, and other ways of knowing are integrated. Consequences of separating ways of knowing are discussed, as are connections to current research, implications to science education, and ideas for future research. Understanding women scientists' scientific/ spiritual ways of knowing may aid science educators in linking academic science to the life-worlds of students.